Multiple Sclerosis, Blood Flow, and CSF Circulation
نویسندگان
چکیده
منابع مشابه
CSF testing for multiple sclerosis.
New diagnostic criteria for multiple sclerosis (MS) were published in 2001 by McDonald and colleagues. These criteria take account of the clinical features, brain and spinal-cord MRI findings, CSF findings, and visual evoked-potential studies. The McDonald criteria define rigorous MRI requirements but do not define an optimum CSF test for the diagnosis of MS. CSF testing should be optimised, be...
متن کاملAnomalous venous blood flow and iron deposition in multiple sclerosis.
Multiple sclerosis (MS) is primarily an autoimmune disorder of unknown origin. This review focuses iron overload and oxidative stress as surrounding cause that leads to immunomodulation in chronic MS. Iron overload has been demonstrated in MS lesions, as a feature common with other neurodegenerative disorders. However, the recent description of chronic cerebrospinal venous insufficiency (CCSVI)...
متن کاملCSF -- oligoclonal bands in multiple sclerosis.
The present paper is concerned with a correlation between clinical parameters of multiple sclerosis and different agar gel electrophoretical patterns in CSF. The agar gel electrophoresis represents clearly the most sensitive method for the demonstration of oligoclonal bands in CSF.
متن کاملFeasibility of the Use of Combinatorial Chemokine Arrays to Study Blood and CSF in Multiple Sclerosis
Meningeal inflammation, including the presence of semi-organized tertiary lymphoid tissue, has been associated with cortical pathology at autopsy in secondary progressive multiple sclerosis (SPMS). Accessible and robust biochemical markers of cortical inflammation for use in SPMS clinical trials are needed. Increased levels of chemokines in the cerebrospinal fluid (CSF) can report on inflammato...
متن کاملBlood and CSF Biomarker Dynamics in Multiple Sclerosis: Implications for Data Interpretation
Background. Disability in multiple sclerosis (MS) is related to neuroaxonal degeneration. A reliable blood biomarker for neuroaxonal degeneration is needed. Objectives. To explore the relationship between cerebrospinal fluid (CSF) and serum concentrations of a protein biomarker for neuroaxonal degeneration, the neurofilaments heavy chain (NfH). Methods. An exploratory cross-sectional (n = 51) a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2013
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.2013.96